Leukocyte Antigen G (HLA-G) Antibody

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Catalogue No: abx239943
Price: US$406.00
(Size: 100 µg)
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WB analysis of human placenta tissue, using HLA-G antibody (1/5000 dilution).
Leukocyte Antigen G (HLA-G) Antibody Leukocyte Antigen G (HLA-G) Antibody

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Leukocyte Antigen G (HLA-G) Antibody is a Mouse Monoclonal antibody for the detection of HLA-G.

Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.

Target Leukocyte Antigen G (HLA-G)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Mouse
Recommended dilutions WB: 1/2000 - 1/10000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen MHC class I antigen G
Isotype IgG1
Form Liquid
Purity ≥ 95% (SDS-PAGE)
Purification Purified by Protein A and Protein G affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity 12 months.
UniProt Primary AC P17693 (UniProt, ExPASy)
UniProt Entry Name HLAG_HUMAN
Gene Symbol HLA-G
GeneID 3135
KEGG hsa:3135
String 9606.ENSP00000412927
Molecular Weight Observed MW: 38 kDa
Buffer PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration 2 mg/ml
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Leukocyte Antigen G (HLA-G)
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