Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4) Antibody

Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4) Antibody is a Rabbit Polyclonal antibody for the detection of LILRB4.

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Leukocyte immunoglobulin-like receptor subfamily B member 4
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q8NHJ6 (UniProt, ExPASy)
UniProt Secondary AC	A8MVL8, O15468, O75021, Q6FGQ9, Q8N1C7, Q8NHL5
UniProt Entry Name	LIRB4_HUMAN
KEGG	hsa:11006
String	9606.ENSP00000375616
Molecular Weight	Observed MW: 49 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4)

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