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Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4) Antibody
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Catalogue No: abx026707
Price:
US$326.25
(Size: 80 µl)
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This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4)
| Target | Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human LILRB4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8NHJ6 (UniProt, ExPASy) |
| UniProt Secondary AC | A8MVL8, O15468, O75021, Q6FGQ9, Q8N1C7, Q8NHL5 |
| UniProt Entry Name | LIRB4_HUMAN |
| Gene Symbol | LILRB4 |
| KEGG | hsa:11006 |
| String | 9606.ENSP00000375616 |
| Molecular Weight | Calculated MW: 49.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |