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LIM Domain Kinase 1 (LIMK1) Antibody
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Catalogue No: abx025221
Price:
US$326.25
(Size: 80 µl)
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Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
Research Articles on LIM Domain Kinase 1 (LIMK1)
| Target | LIM Domain Kinase 1 (LIMK1) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 479-508 amino acids from the C-terminal region of human LIMK1. |
| Isotype | IgM Kappa |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P53667 (UniProt, ExPASy) |
| UniProt Entry Name | LIMK1_HUMAN |
| KEGG | hsa:3984 |
| String | 9606.ENSP00000336740 |
| Molecular Weight | Calculated MW: 72.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |