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LIM Zinc Finger Domain Containing 1 (LIMS1) Antibody
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Catalogue No: abx004882
Price:
US$203.00
(Size: 20 µl)
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LIMS1 Antibody is a Rabbit Polyclonal antibody against LIMS1. The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
Research Articles on LIM Zinc Finger Domain Containing 1 (LIMS1)
| Target | LIM Zinc Finger Domain Containing 1 (LIMS1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human LIMS1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48059 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RAJ4, B7Z483, B7Z7R3, B7Z907, Q53TE0, Q9BS44 |
| UniProt Entry Name | LIMS1_HUMAN |
| Gene Symbol | LIMS1 |
| GeneID | 3987 |
| NCBI Accession | NP_001180417.1 |
| KEGG | hsa:3987 |
| String | 9606.ENSP00000446121 |
| Molecular Weight | Calculated MW: 37 kDa Observed MW: 40 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |