Protein Lin-7 Homolog A (LIN7A) Antibody

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Catalogue No: abx029388
Price: US$326.25
(Size: 80 µl)

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Protein Lin-7 Homolog A (LIN7A) Antibody
Protein Lin-7 Homolog A (LIN7A) Antibody

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Datasheet SDS
LIN7A plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

Target Protein Lin-7 Homolog A (LIN7A)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 180-207 amino acids from the C-terminal region of human LIN7A.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O14910 (UniProt, ExPASy)
UniProt Secondary AC A4FTY3, Q147W1, Q6LES3, Q7LDS4
UniProt Entry Name LIN7A_HUMAN
Gene Symbol LIN7A
KEGG hsa:8825
String 9606.ENSP00000447488
Molecular Weight Calculated MW: 26 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse, Rat and Cow LIN7A.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Protein Lin-7 Homolog A (LIN7A)
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