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Leucine-Rich Repeat Neuronal Protein 1 (LINGO1) Antibody
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Catalogue No: abx033300
Price:
US$290.00
(Size: 80 µl)
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LINGO1 is a functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.
Research Articles on Leucine-Rich Repeat Neuronal Protein 1 (LINGO1)
| Target | Leucine-Rich Repeat Neuronal Protein 1 (LINGO1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/400. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 62-92 amino acids from the N-terminal region of human LINGO1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96FE5 (UniProt, ExPASy) |
| UniProt Entry Name | LIGO1_HUMAN |
| KEGG | hsa:84894 |
| String | 9606.ENSP00000347451 |
| Molecular Weight | Calculated MW: 69.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Chicken and Monkey LINGO1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |