+44 (0) 1223 755950
+1 832 327 7413
Human Lipoprotein Lipase (LPL) Protein
REQUEST MORE INFO
Catalogue No: abx073909
Price:
US$261.00
(Size: 2 µg)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Human Lipoprotein Lipase (LPL) Enzyme is a recombinant enzyme produced in HEK cells. LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008].
Research Articles on Lipoprotein Lipase (LPL)
| Target | Lipoprotein Lipase (LPL) |
| Target Modification | Mutation |
| Modification | Asn318Ser |
| Origin | Human |
| Expression | Recombinant |
| Host | HEK293 cells |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Form | Lyophilized |
| Purification | 0.4 µm filtered prior to lyophilization. Non-sterile. |
| Reconstitution | Reconstitute in deionized water to a concentration of 0.5 mg/ml. Filter using a sterile filter prior to use in cell culture. |
| Storage | Store lyophilized at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. |
| UniProt Primary AC | P06858 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R5T9, Q16282, Q16283, Q96FC4 |
| UniProt Entry Name | LIPL_HUMAN |
| KEGG | hsa:4023 |
| String | 9606.ENSP00000309757 |
| Molecular Weight | 51.8 kDa |
| Sequence | HVDYKDDDDK PAGADQ RRDFIDIESK FALRTPEDTA EDTCHLIPGV AESVATCHFN HSSKTFMVIH GWTVTGMYES WVPKLVAALY KREPDSNVIV VDWLSRAQEH YPVSAGYTKL VGQDVARFIN WMEEEFNYPL DNVHLLGYSL GAHAAGIAGS LTNKKVNRIT GLDPAGPNFE YAEAPSRLSP DDADFVDVLH TFTRGSPGRS IGIQKPVGHV DIYPNGGTFQ PGCNIGEAIR VIAERGLGDV DQLVKCSHER SIHLFIDSLL NEENPSKAYR CSSKEAFEKG LCLSCRKNRC NNLGYEINKV RAKRSSKMYL KTRSQMPYKV FHYQVKIHFS GTESETHTNQ AFEISLYGTV AESENIPFTL PEVSTNKTYS FLIYTEVDIG ELLMLKLKWK SDSYFSWSDW WSSPGFAIQK IRVKAGETQK KVIFCSREKV SHLQKGKAPA VFVKCHDKSL NKKSG |
| Tag | N-terminal Flag tag |
| Buffer | Prior to lyophilization: 20 mM Tris, 50 mM NaCl, pH 7.5 |
| Activity | Not tested |
| Concentration | Prior to lyophilization: 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |