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Lymphocyte-Oriented Kinase (LOK) Antibody
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Catalogue No: abx033789
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.
Research Articles on Lymphocyte-Oriented Kinase (LOK)
| Target | Lymphocyte-Oriented Kinase (LOK) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human LOK. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O94804 (UniProt, ExPASy) |
| UniProt Secondary AC | A6ND35, B2R8F5, B3KMY1, Q6NSK0, Q9UIW4 |
| UniProt Entry Name | STK10_HUMAN |
| KEGG | hsa:6793 |
| String | 9606.ENSP00000176763 |
| Molecular Weight | Calculated MW: 112 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |