+44 (0) 1223 755950
+1 832 327 7413
Lon Protease Homolog, Mitochondrial (LONP1) Antibody
REQUEST MORE INFO
Catalogue No: abx003188
Price:
US$217.50
(Size: 20 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
LONP1 Antibody is a Rabbit Polyclonal antibody against LONP1. This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene.
Research Articles on Lon Protease Homolog, Mitochondrial (LONP1)
| Target | Lon Protease Homolog, Mitochondrial (LONP1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human LONP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P36776 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KPH8, D6W635, E5KMH8, F5GZ27, P36777, Q8N8K8, Q9UQ95 |
| UniProt Entry Name | LONM_HUMAN |
| Gene Symbol | LONP1 |
| GeneID | 9361 |
| NCBI Accession | NP_004784.2 |
| KEGG | hsa:9361 |
| String | 9606.ENSP00000353826 |
| Molecular Weight | Calculated MW: 106 kDa Observed MW: 106 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |