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Low Density Lipoprotein Receptor (LDLR) Antibody
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Catalogue No: abx240262
Price:
US$406.00
(Size: 100 µg)
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Low Density Lipoprotein Receptor (LDLR) Antibody is a Rabbit Polyclonal antibody for the detection of LDLR. LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.
Research Articles on Low Density Lipoprotein Receptor (LDLR)
| Target | Low Density Lipoprotein Receptor (LDLR) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | low density lipoprotein receptor |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P01130 (UniProt, ExPASy) |
| UniProt Entry Name | LDLR_HUMAN |
| Gene Symbol | LDLR |
| GeneID | 3949 |
| OMIM | 143890 |
| HGNC | 6547 |
| KEGG | hsa:3949 |
| Ensembl | ENSG00000130164 |
| String | 9606.ENSP00000454071 |
| Molecular Weight | Observed MW: 100-160 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |