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Protein-Lysine 6-Oxidase (LOX) Antibody
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Catalogue No: abx025524
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Protein-Lysine 6-Oxidase (LOX)
| Target | Protein-Lysine 6-Oxidase (LOX) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX. |
| Isotype | IgG2b |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P28300 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R5Q3, Q5FWF0 |
| UniProt Entry Name | LYOX_HUMAN |
| KEGG | hsa:4015 |
| String | 9606.ENSP00000231004 |
| Molecular Weight | Calculated MW: 46.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Pig LOX. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |