Lysyl Oxidase Like 2 (LOXL2) Antibody

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Target	Lysyl Oxidase Like 2 (LOXL2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 589-617 amino acids from the C-terminal region of human LOXL2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y4K0 (UniProt, ExPASy)
UniProt Secondary AC	B2R5Q0, Q53HV3, Q9BW70, Q9Y5Y8
UniProt Entry Name	LOXL2_HUMAN
Gene Symbol	LOXL2
String	9606.ENSP00000373783
Molecular Weight	Calculated MW: 86.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat, Cow and Chicken LOXL2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Lysyl Oxidase Like 2 (LOXL2)

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