Lysyl Oxidase Like 2 (LOXL2) Antibody

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Catalogue No: abx028616
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Target Lysyl Oxidase Like 2 (LOXL2)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 589-617 amino acids from the C-terminal region of human LOXL2.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9Y4K0 (UniProt, ExPASy)
UniProt Secondary AC B2R5Q0, Q53HV3, Q9BW70, Q9Y5Y8
UniProt Entry Name LOXL2_HUMAN
Gene Symbol LOXL2
String 9606.ENSP00000373783
Molecular Weight Calculated MW: 86.7 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse, Rat, Cow and Chicken LOXL2.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Lysyl Oxidase Like 2 (LOXL2)