Lecithin Retinol Acyltransferase (LRAT) Antibody

LRAT Antibody is a Rabbit Polyclonal antibody against LRAT. The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.

Target	Lecithin Retinol Acyltransferase (LRAT)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human LRAT.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O95237 (UniProt, ExPASy)
UniProt Secondary AC	A8K983, Q8N716
UniProt Entry Name	LRAT_HUMAN
Gene Symbol	LRAT
GeneID	9227
NCBI Accession	NP_004735.2
KEGG	hsa:9227
String	9606.ENSP00000337224
Molecular Weight	Calculated MW: 26 kDa Observed MW: 24 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Lecithin Retinol Acyltransferase (LRAT)

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