Prolow-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Antibody

LRP1 Antibody is a Rabbit Polyclonal antibody against LRP1. The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. [provided by RefSeq, Jan 2010].

Target	Prolow-Density Lipoprotein Receptor-Related Protein 1 (LRP1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 4401-4500 of LRP1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q07954 (UniProt, ExPASy)
UniProt Secondary AC	Q2PP12, Q86SW0, Q8IVG8
UniProt Entry Name	LRP1_HUMAN
Gene Symbol	LRP1
GeneID	4035
NCBI Accession	NP_002323.2
KEGG	hsa:4035
String	9606.ENSP00000243077
Molecular Weight	Calculated MW: 505 kDa Observed MW: 505 kDa
Buffer	PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Prolow-Density Lipoprotein Receptor-Related Protein 1 (LRP1)

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