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Lymphotoxin Beta (LTB) Antibody
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Catalogue No: abx025385
Price:
US$290.00
(Size: 80 µl)
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Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on Lymphotoxin Beta (LTB)
| Target | Lymphotoxin Beta (LTB) |
| Clonality | Monoclonal |
| Clone | F113 |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 199-227 amino acids from the C-terminal region of human LTB. |
| Isotype | IgM |
| Form | Liquid |
| Purification | Purified by euglobulin precipitation followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q06643 (UniProt, ExPASy) |
| UniProt Secondary AC | P78370, Q52LU8, Q99761 |
| UniProt Entry Name | TNFC_HUMAN |
| KEGG | hsa:4050 |
| String | 9606.ENSP00000410481 |
| Molecular Weight | Calculated MW: 25.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Pig LTB. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |