Lymphotoxin Beta (LTB) Antibody

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Catalogue No: abx025385
Price: US$326.25
(Size: 80 µl)

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WB analysis of HL-60 cell line lysates.
Lymphotoxin Beta (LTB) Antibody

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Datasheet SDS
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target Lymphotoxin Beta (LTB)
Clonality Monoclonal
Clone F113
Reactivity Human
Tested Applications ELISA, WB
Host Mouse
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 199-227 amino acids from the C-terminal region of human LTB.
Isotype IgM
Form Liquid
Purification Purified by euglobulin precipitation followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q06643 (UniProt, ExPASy)
UniProt Secondary AC P78370, Q52LU8, Q99761
UniProt Entry Name TNFC_HUMAN
KEGG hsa:4050
String 9606.ENSP00000410481
Molecular Weight Calculated MW: 25.4 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Pig LTB.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Lymphotoxin Beta (LTB)
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