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Lymphotoxin Alpha (LTA) Antibody
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Catalogue No: abx001306
Price:
US$203.00
(Size: 20 µl)
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LTA Antibody is a Rabbit Polyclonal antibody against LTA. The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.
Research Articles on Lymphotoxin Alpha (LTA)
| Target | Lymphotoxin Alpha (LTA) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 35-205 of human LTA. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P01374 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8N4C3, Q9UKS8 |
| UniProt Entry Name | TNFB_HUMAN |
| GeneID | 4049 |
| NCBI Accession | NP_000586.2 |
| KEGG | hsa:4049 |
| String | 9606.ENSP00000403495 |
| Molecular Weight | Calculated MW: 22 kDa Observed MW: 22 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |