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Lysyl Oxidase Like Protein 2 (LOXL2) Antibody
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Catalogue No: abx240158
Price:
US$406.00
(Size: 100 µg)
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Lysyl Oxidase Like Protein 2 (LOXL2) Antibody is a Rabbit Polyclonal antibody for the detection of LOXL2. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Research Articles on Lysyl Oxidase Like Protein 2 (LOXL2)
| Target | Lysyl Oxidase Like Protein 2 (LOXL2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Lysyl oxidase homolog 2 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q9Y4K0 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R5Q0, Q53HV3, Q9BW70, Q9Y5Y8 |
| UniProt Entry Name | LOXL2_HUMAN |
| String | 9606.ENSP00000373783 |
| Molecular Weight | Observed MW: 87-100 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |