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Leucine Zipper Tumor Suppressor 1 (LZTS1) Antibody
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Catalogue No: abx027187
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
Research Articles on Leucine Zipper Tumor Suppressor 1 (LZTS1)
| Target | Leucine Zipper Tumor Suppressor 1 (LZTS1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 77-105 amino acids from the N-terminal region of human LZTS1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y250 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DSQ6, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2 |
| UniProt Entry Name | LZTS1_HUMAN |
| Gene Symbol | LZTS1 |
| NCBI Accession | NP_066300.1 |
| String | 9606.ENSP00000370981 |
| Molecular Weight | Calculated MW: 66.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |