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M Gpr68 Antibody
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Catalogue No: abx034939
Price:
US$326.25
(Size: 80 µl)
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Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca (2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
Research Articles on M Gpr68
| Target | M Gpr68 |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 200-225 amino acids from the Central region of mouse Gpr68. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8BFQ3 (UniProt, ExPASy) |
| UniProt Secondary AC | Q148P7, Q3U1L3, Q80T34 |
| UniProt Entry Name | OGR1_MOUSE |
| NCBI Accession | NP_001171144.1 NP_001171145.1 NP_780702.1 |
| KEGG | mmu:238377 |
| String | 10090.ENSMUSP00000105693 |
| Molecular Weight | Calculated MW: 41.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Human and Cow Gpr68. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |