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M Sirt3 Antibody
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Catalogue No: abx032748
Price:
US$326.25
(Size: 50 µl)
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SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.
Research Articles on M Sirt3
| Target | M Sirt3 |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 225-253 amino acids from the C-terminal region of Mouse Sirt3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8R104 (UniProt, ExPASy) |
| UniProt Secondary AC | B9W0A9, C6ZII7, Q9EPA8 |
| UniProt Entry Name | SIR3_MOUSE |
| NCBI Accession | NP_001120823.1 NP_001171275.1 NP_071878.2 |
| KEGG | mmu:64384 |
| String | 10090.ENSMUSP00000026559 |
| Molecular Weight | Calculated MW: 36.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |