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Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) Antibody
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Catalogue No: abx028819
Price:
US$290.00
(Size: 80 µl)
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Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Research Articles on Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF)
| Target | Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 23-51 amino acids from the N-terminal region of human MANF. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P55145 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14CX4, Q86U67, Q96IS4 |
| UniProt Entry Name | MANF_HUMAN |
| GeneID | 7873 |
| KEGG | hsa:7873 |
| String | 9606.ENSP00000432799 |
| Molecular Weight | Calculated MW: 20.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Cow MANF. |
| Concentration | 0.4 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |