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Dual Specificity Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) Antibody
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Catalogue No: abx005276
Price:
US$348.00
(Size: 60 µl)
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MAP2K5 Antibody is a Rabbit Polyclonal antibody against MAP2K5. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
Research Articles on Dual Specificity Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5)
| Target | Dual Specificity Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human MAP2K5 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13163 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DE43, Q92961, Q92962 |
| UniProt Entry Name | MP2K5_HUMAN |
| Gene Symbol | MAP2K5 |
| GeneID | 5607 |
| NCBI Accession | NP_660143.1 |
| KEGG | hsa:5607 |
| String | 9606.ENSP00000178640 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
