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MAP3K7 (pT187) Antibody
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Catalogue No: abx031943
Price:
US$326.25
(Size: 80 µl)
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MAP3K7 is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.
Research Articles on MAP3K7 (pT187)
| Target | MAP3K7 (pT187) |
| Clonality | Polyclonal |
| Target Modification | Thr187 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T187 of human MAP3K7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by protein A affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with peptides. The antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O43318 (UniProt, ExPASy) |
| UniProt Entry Name | M3K7_HUMAN |
| KEGG | hsa:6885 |
| String | 9606.ENSP00000358335 |
| Molecular Weight | Calculated MW: 67.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Cow MAP3K7. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |