Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Antibody

The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

Target	Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 321-349 amino acids from the Central region of human MAP4K2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q12851 (UniProt, ExPASy)
UniProt Secondary AC	Q86VU3
UniProt Entry Name	M4K2_HUMAN
Gene Symbol	MAP4K2
GeneID	5871
OMIM	603166
HGNC	6864
KEGG	hsa:5871
Ensembl	ENSG00000168067
String	9606.ENSP00000294066
Molecular Weight	Calculated MW: 91.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse MAP4K2.
Concentration	0.5 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2)

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