MEK Kinase Kinase 3 (MAP4K3) Antibody

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Catalogue No: abx025273
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
This gene encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).

Target MEK Kinase Kinase 3 (MAP4K3)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Mouse
Recommended dilutions WB: 1/500 - 1/1000, IHC-P: 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Human MAP4K3 recombinant protein.
Isotype IgM Kappa
Form Liquid
Purification Purified Mouse Monoclonal Antibody.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q8IVH8 (UniProt, ExPASy)
UniProt Secondary AC Q6IQ39, Q8IVH7, Q9UDM5, Q9Y6R5
UniProt Entry Name M4K3_HUMAN
KEGG hsa:8491
String 9606.ENSP00000263881
Molecular Weight Calculated MW: 101 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on MEK Kinase Kinase 3 (MAP4K3)


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