MAP4K4 (pS801) Antibody

M4K4, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.

Target	MAP4K4 (pS801)
Clonality	Polyclonal
Target Modification	Ser801
Modification	Phosphorylation
Reactivity	Human
Tested Applications	ELISA, DB
Host	Rabbit
Recommended dilutions	DB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S801 of human MAP4K4.
Isotype	IgG
Form	Liquid
Purification	Purified in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O95819 (UniProt, ExPASy)
UniProt Secondary AC	E7ESS2, O75172, Q9NST7
UniProt Entry Name	M4K4_HUMAN
KEGG	hsa:9448
String	9606.ENSP00000343658
Molecular Weight	Calculated MW: 142 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on MAP4K4 (pS801)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue