Melanoma Antigen Preferentially Expressed In Tumors (PRAME) Antibody

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Catalogue No: abx032957
Price: US$326.25
(Size: 80 µl)
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WB analysis of (1) HeLa whole cell lysate, (2) K562 whole cell lysate, (3) 293 whole cell lysate, (4) human testis lysate, (5) human brain lysate, and (6) human kidney lysate (20 µg/lane, predicted band size: 58 kDa).
Melanoma Antigen Preferentially Expressed In Tumors (PRAME) Antibody Melanoma Antigen Preferentially Expressed In Tumors (PRAME) Antibody Melanoma Antigen Preferentially Expressed In Tumors (PRAME) Antibody

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Datasheet SDS
MAPE is an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, its gene is also expressed in acute leukemias.

Target Melanoma Antigen Preferentially Expressed In Tumors (PRAME)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, FCM
Host Rabbit
Recommended dilutions WB: 1/2000, IHC-P: 1/50 - 1/100, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 476-502 amino acids from the C-terminal region of human MAPE.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P78395 (UniProt, ExPASy)
UniProt Secondary AC B2R6Y7, O43481, Q8IXN8
UniProt Entry Name PRAME_HUMAN
Gene Symbol PRAME
GeneID 23532
OMIM 606021
NCBI Accession NP_006106.1 NP_996836.1 NP_996837.1 NP_996838.1 NP_996839.1
HGNC 9336
KEGG hsa:23532
Ensembl ENSG00000185686
String 9606.ENSP00000445675
Molecular Weight Calculated MW: 57.9 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Melanoma Antigen Preferentially Expressed In Tumors (PRAME)
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