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Mitogen-Activated Protein Kinase 9 / JNK2 (MAPK9) Antibody
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Catalogue No: abx001162
Price:
US$232.00
(Size: 20 µl)
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MAPK9 Antibody is a Rabbit Polyclonal antibody against MAPK9. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Research Articles on Mitogen-Activated Protein Kinase 9 / JNK2 (MAPK9)
| Target | Mitogen-Activated Protein Kinase 9 / JNK2 (MAPK9) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-424 of human JNK2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P45984 (UniProt, ExPASy) |
| UniProt Entry Name | MK09_HUMAN |
| Gene Symbol | MAPK9 |
| GeneID | 5601 |
| NCBI Accession | NP_002743.3 |
| KEGG | hsa:5601 |
| String | 9606.ENSP00000394560 |
| Molecular Weight | Calculated MW: 48 kDa Observed MW: 54 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |