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MAP Kinase-Activated Protein Kinase 5 Phospho-Ser93 (MAPKAPK5 pS93) Antibody
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Catalogue No: abx031875
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites.
Research Articles on MAP Kinase-Activated Protein Kinase 5 Phospho-Ser93 (MAPKAPK5 pS93)
| Target | MAP Kinase-Activated Protein Kinase 5 Phospho-Ser93 (MAPKAPK5 pS93) |
| Clonality | Polyclonal |
| Target Modification | Ser93 |
| Modification | Phosphorylation |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S93 of human MAPKAPK5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8IW41 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KVA5, O60491, Q86X46, Q9BVX9, Q9UG86 |
| UniProt Entry Name | MAPK5_HUMAN |
| NCBI Accession | NP_003659.2 NP_620777.1 |
| KEGG | hsa:8550 |
| String | 9606.ENSP00000449381 |
| Molecular Weight | Calculated MW: 54.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |