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Microtubule-Associated Protein Tau (MAPT) Antibody
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Catalogue No: abx001022
Price:
US$203.00
(Size: 20 µl)
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MAPT Antibody is a Rabbit Polyclonal antibody against MAPT. This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Research Articles on Microtubule-Associated Protein Tau (MAPT)
| Target | Microtubule-Associated Protein Tau (MAPT) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IHC-P: 1/100 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 658-758 of human Tau. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P10636 (UniProt, ExPASy) |
| UniProt Secondary AC | P18518, Q14799, Q15549, Q15550, Q15551, Q1RMF6, Q53YB1, Q5CZI7, Q5XWF0, Q6QT54, Q9UDJ3, Q9UMH0, Q9UQ96 |
| UniProt Entry Name | TAU_HUMAN |
| Gene Symbol | MAPT |
| GeneID | 4137 |
| OMIM | 157140 |
| NCBI Accession | NP_058519.3 |
| HGNC | 6893 |
| KEGG | hsa:4137 |
| Ensembl | ENSG00000186868 |
| String | 9606.ENSP00000340820 |
| Molecular Weight | Calculated MW: 79 kDa Observed MW: 45-75 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |