Membrane Associated Ring-CH-Type Finger 4 (MARCHF4) Antibody

Membrane Associated Ring-CH-Type Finger 4 (MARCHF4) is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCHF4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).

Target	Membrane Associated Ring-CH-Type Finger 4 (MARCHF4)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 302-331 amino acids from the C-terminal region of human MARCH4.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9P2E8 (UniProt, ExPASy)
UniProt Secondary AC	Q4KMN7, Q86WR8
UniProt Entry Name	MARH4_HUMAN
String	9606.ENSP00000273067
Molecular Weight	Calculated MW: 45.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Membrane Associated Ring-CH-Type Finger 4 (MARCHF4)

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