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Myelin Basic Protein (MBP) Antibody
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Catalogue No: abx001398
Price:
US$348.00
(Size: 60 µl)
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MBP Antibody is a Rabbit Polyclonal antibody against MBP. MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. This is a rabbit polyclonal antibody raised against the full-length of human MBP,and is capable of recognizing multiple isoforms of MBP.
Research Articles on Myelin Basic Protein (MBP)
| Target | Myelin Basic Protein (MBP) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human Myelin Basic protein |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P02686 (UniProt, ExPASy) |
| UniProt Entry Name | MBP_HUMAN |
| Gene Symbol | MBP |
| GeneID | 4155 |
| NCBI Accession | NP_001020272.1 |
| KEGG | hsa:4155 |
| String | 9606.ENSP00000380958 |
| Molecular Weight | Calculated MW: 17 kDa/18 kDa/20 kDa/21 kDa/33 kDa Observed MW: 17 kDa/33 kDa/40 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |