MCA1 Antibody

MCA1 is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.

Target	MCA1
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 242-268 amino acids from the C-terminal region of human MCA1.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q12904 (UniProt, ExPASy)
UniProt Secondary AC	B3KTR2, B4E1S7, Q6FG28, Q96CQ9
UniProt Entry Name	AIMP1_HUMAN
KEGG	hsa:9255
String	9606.ENSP00000378191
Molecular Weight	Calculated MW: 34.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Hamster AIMP1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on MCA1

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