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Activating Transcription Factor 7-Interacting Protein 2 (ATF7IP2) Antibody
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Catalogue No: abx025751
Price:
US$326.25
(Size: 80 µl)
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ATF7IP2/MCAF2 is a recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).
Research Articles on Activating Transcription Factor 7-Interacting Protein 2 (ATF7IP2)
| Target | Activating Transcription Factor 7-Interacting Protein 2 (ATF7IP2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 318-347 amino acids from the central region of human MCAF2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q5U623 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RNR2, Q53EZ7, Q658U2, Q6IS97, Q8N9X8, Q9H9L6 |
| UniProt Entry Name | MCAF2_HUMAN |
| KEGG | hsa:80063 |
| String | 9606.ENSP00000379808 |
| Molecular Weight | Calculated MW: 75.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |