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Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody
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Catalogue No: abx011122
Price:
US$427.75
(Size: 100 µl)
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Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF alpha 1 and forskolin.
Research Articles on Induced Myeloid Leukemia Cell Differentiation Protein (MCL1)
| Target | Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human MCL-1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q07820 (UniProt, ExPASy) |
| UniProt Entry Name | MCL1_HUMAN |
| Gene Symbol | MCL1 |
| GeneID | 4170 |
| OMIM | 159552 |
| HGNC | 6943 |
| KEGG | hsa:4170 |
| Ensembl | ENSG00000143384 |
| String | 9606.ENSP00000358022 |
| Molecular Weight | 37 kDa |
| Buffer | PBS, containing 0.03% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |