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DNA Replication Licensing Factor MCM2 (MCM2) Antibody
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Catalogue No: abx000979
Price:
US$203.00
(Size: 20 µl)
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MCM2 Antibody is a Rabbit Polyclonal antibody against MCM2. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Research Articles on DNA Replication Licensing Factor MCM2 (MCM2)
| Target | DNA Replication Licensing Factor MCM2 (MCM2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 360-700 of human MCM2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49736 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7 |
| UniProt Entry Name | MCM2_HUMAN |
| Gene Symbol | MCM2 |
| GeneID | 4171 |
| NCBI Accession | NP_004517.2 |
| KEGG | hsa:4171 |
| String | 9606.ENSP00000265056 |
| Molecular Weight | Calculated MW: 102 kDa Observed MW: 130 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |