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Minichromosome Maintenance Deficient 3 (MCM3) Antibody
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Catalogue No: abx027744
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq].
Research Articles on Minichromosome Maintenance Deficient 3 (MCM3)
| Target | Minichromosome Maintenance Deficient 3 (MCM3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human MCM3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P25205 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DWW4, Q92660, Q9BTR3, Q9NUE7 |
| UniProt Entry Name | MCM3_HUMAN |
| Gene Symbol | MCM3 |
| KEGG | hsa:4172 |
| String | 9606.ENSP00000480987 |
| Molecular Weight | Calculated MW: 91 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Cow MCM3. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |