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MCM8 Minichromosome Maintenance Deficient 8 (MCM8) Antibody
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Catalogue No: abx029507
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Research Articles on MCM8 Minichromosome Maintenance Deficient 8 (MCM8)
| Target | MCM8 Minichromosome Maintenance Deficient 8 (MCM8) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 322-350 amino acids from the Central region of human MCM8. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UJA3 (UniProt, ExPASy) |
| UniProt Entry Name | MCM8_HUMAN |
| Gene Symbol | MCM8 |
| String | 9606.ENSP00000368164 |
| Molecular Weight | Calculated MW: 93.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |