Mucolipin 1 (MCOLN1) Antibody

This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca (2+), Fe (2+), Na (+), K (+), and H (+), and is modulated by changes in Ca (2+) concentration. Mutations in this gene result in mucolipidosis type IV.

Target	Mucolipin 1 (MCOLN1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 531-560 amino acids from the C-terminal region of human MCOLN1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9GZU1 (UniProt, ExPASy)
UniProt Secondary AC	D6W647, Q7Z4F7, Q9H292, Q9H4B3, Q9H4B5
UniProt Entry Name	MCLN1_HUMAN
Gene Symbol	MCOLN1
String	9606.ENSP00000264079
Molecular Weight	Calculated MW: 65 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Monkey MCOLN1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mucolipin 1 (MCOLN1)

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