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Microcephalin (MCPH1) Antibody
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Catalogue No: abx027884
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.
Research Articles on Microcephalin (MCPH1)
| Target | Microcephalin (MCPH1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human MCPH1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8NEM0 (UniProt, ExPASy) |
| UniProt Secondary AC | A0A075B6F8, B4DWW2, E9PGU5, E9PH63, Q66GU1, Q9H9C7 |
| UniProt Entry Name | MCPH1_HUMAN |
| Gene Symbol | MCPH1 |
| KEGG | hsa:79648 |
| String | 9606.ENSP00000342924 |
| Molecular Weight | Calculated MW: 92.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Monkey MCPH1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |