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Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) Antibody
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Catalogue No: abx026916
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq].
Research Articles on Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2)
| Target | Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 527-556 amino acids from the C-terminal region of human ME2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P23368 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R8J2, Q9BWL6, Q9BYG1, Q9H4B2 |
| UniProt Entry Name | MAOM_HUMAN |
| Gene Symbol | ME2 |
| KEGG | hsa:4200 |
| String | 9606.ENSP00000321070 |
| Molecular Weight | Calculated MW: 65.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |