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MDS1 And EVI1 Complex Locus Protein EVI1 (MECOM) Antibody
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Catalogue No: abx004339
Price:
US$217.50
(Size: 20 µl)
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MECOM Antibody is a Rabbit Polyclonal antibody against MECOM. The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Research Articles on MDS1 And EVI1 Complex Locus Protein EVI1 (MECOM)
| Target | MDS1 And EVI1 Complex Locus Protein EVI1 (MECOM) |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MECOM. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q03112 (UniProt, ExPASy) |
| UniProt Secondary AC | A1L4F3, A8KA00, B7Z8W7, B7ZLQ3, B7ZLQ4, C9JAK0, D3DNP7, E7EQ57, Q13465, Q13466, Q16122, Q5HYI1, Q6FH90, Q6MZS6, Q8NEI5, Q99917 |
| Gene Symbol | MECOM |
| GeneID | 2122 |
| NCBI Accession | NP_004982.2 |
| Molecular Weight | Calculated MW: 18/117/118/125/139 kDa Observed MW: 105/145 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |