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UK +44 (0) 1223 755950 US +1 832 327 7413 @
Mediator Complex Subunit 14 (MED14) Antibody
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Catalogue No: abx026654
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
Research Articles on Mediator Complex Subunit 14 (MED14)
| Target | Mediator Complex Subunit 14 (MED14) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/4000, FCM: 1/25. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 586-615 amino acids from the Central region of human MED14. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60244 (UniProt, ExPASy) |
| UniProt Secondary AC | Q4KMR7, Q9UNB3 |
| UniProt Entry Name | MED14_HUMAN |
| Gene Symbol | MED14 |
| KEGG | hsa:9282 |
| String | 9606.ENSP00000323720 |
| Molecular Weight | Calculated MW: 161 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
