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Protein-Tyrosine Phosphatase MEG2 (MEG2) Antibody
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Catalogue No: abx033937
Price:
US$290.00
(Size: 80 µl)
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MEG2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.
Research Articles on Protein-Tyrosine Phosphatase MEG2 (MEG2)
| Target | Protein-Tyrosine Phosphatase MEG2 (MEG2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 477-505 amino acids from the C-terminal region of human MEG2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P43378 (UniProt, ExPASy) |
| UniProt Secondary AC | Q53XR9 |
| UniProt Entry Name | PTN9_HUMAN |
| KEGG | hsa:5780 |
| String | 9606.ENSP00000482732 |
| Molecular Weight | Calculated MW: 68 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |