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Tyrosine-Protein Kinase Mer (MERTK) Antibody
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Catalogue No: abx016037
Price:
US$427.75
(Size: 100 µl)
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MER (c-mer proto-oncogene tyrosine kinase) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain.MER has been identified as a tyrosine kinase potentially involved in the development of glioblastomas.It is expressed at highest levels in ovary, prostate, lung and kidney.Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S have been identified as ligands for the UFO family of receptors.Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
Research Articles on Tyrosine-Protein Kinase Mer (MERTK)
| Target | Tyrosine-Protein Kinase Mer (MERTK) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of MER expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q12866 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9HBB4 |
| UniProt Entry Name | MERTK_HUMAN |
| Gene Symbol | MERTK |
| GeneID | 10461 |
| OMIM | 604705 |
| NCBI Accession | NP_006334.2 |
| HGNC | 7027 |
| KEGG | hsa:10461 |
| Ensembl | ENSG00000153208 |
| String | 9606.ENSP00000295408 |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |