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Tyrosine-Protein Kinase Mer (MERTK) Antibody
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Catalogue No: abx033726
Price:
US$290.00
(Size: 80 µl)
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MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in MERTK gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
Research Articles on Tyrosine-Protein Kinase Mer (MERTK)
| Target | Tyrosine-Protein Kinase Mer (MERTK) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | His-tagged recombinant human MERTK. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q12866 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9HBB4 |
| UniProt Entry Name | MERTK_HUMAN |
| Gene Symbol | MERTK |
| GeneID | 10461 |
| OMIM | 604705 |
| NCBI Accession | NP_006334.2 |
| HGNC | 7027 |
| KEGG | hsa:10461 |
| Ensembl | ENSG00000153208 |
| String | 9606.ENSP00000295408 |
| Molecular Weight | Calculated MW: 110 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |