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Metadherin (MTDH) Antibody
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Catalogue No: abx240125
Price:
US$406.00
(Size: 100 µg)
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Metadherin (MTDH) Antibody is a Rabbit Polyclonal antibody for the detection of AEG-1. MTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22, the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma, and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression. This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH.
Research Articles on Metadherin (MTDH)
| Target | Metadherin (MTDH) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | metadherin |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q86UE4 (UniProt, ExPASy) |
| UniProt Secondary AC | Q05DH2, Q52QU9, Q6PK07, Q8TCX3 |
| UniProt Entry Name | LYRIC_HUMAN |
| Gene Symbol | MTDH |
| GeneID | 92140 |
| OMIM | 610323 |
| HGNC | 29608 |
| KEGG | hsa:92140 |
| Ensembl | ENSG00000147649 |
| String | 9606.ENSP00000338235 |
| Molecular Weight | Observed MW: 64-80 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |