+44 (0) 1223 755950
+1 832 327 7413
Methionine Aminopeptidase 2 (METAP2) Antibody
REQUEST MORE INFO
Catalogue No: abx028022
Price:
US$326.25
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2.
Research Articles on Methionine Aminopeptidase 2 (METAP2)
| Target | Methionine Aminopeptidase 2 (METAP2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human METAP2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P50579 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RDI8, B4DUX5, G3XA91, Q8NB11 |
| UniProt Entry Name | MAP2_HUMAN |
| KEGG | hsa:10988 |
| String | 9606.ENSP00000325312 |
| Molecular Weight | Calculated MW: 52.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |