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Mitofusin-2 (MFN2) Antibody
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Catalogue No: abx034129
Price:
US$326.25
(Size: 80 µl)
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MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system.
Research Articles on Mitofusin-2 (MFN2)
| Target | Mitofusin-2 (MFN2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/25, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 447-476 amino acids from the Central region of human MFN2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O95140 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K1B3, O95572, Q5JXC3, Q5JXC4, Q9H131, Q9NSX8 |
| UniProt Entry Name | MFN2_HUMAN |
| Gene Symbol | MFN2 |
| KEGG | hsa:9927 |
| String | 9606.ENSP00000235329 |
| Molecular Weight | Calculated MW: 86.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat MFN2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |